Our Solutions

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Our Solutions

Testing Services

At Logical Life Science Pvt Ltd. we offer a diverse portfolio of cell based and biophysical assays that enable the development and characterization of new drug candidates for cancer and other metabolic diseases. Our team of dedicated scientists work closely with you to develop and design assays suitable for your specific research requirements.

Our anti-cancer activity analysis portfolio gives a wide array of experimental choices to the researchers, pharma companies and drug designing/manufacturing companies where they can test the anticancer activities of single molecules/herbal and plant extracts, nano particles, ayurvedic drugs on various cancer cells lines as well as on primary tumor cells of various origins. In our basic anticancer activity analysis portfolio molecules/abstracts can be tested for their effects on cell death (Apoptosis), cell proliferation, cell cycle, free radical generation, and other basic experiments.

Our specialized anticancer activity analysis portfolio tests and screens the drugs/extracts for their activities against cancer stem cell markers, metastatic parameters, effects on epithelial-mesenchymal transitions and effects on tumor immune evasion mechanisms.

The parameters we study are

  • Proliferation, determination of DNA content by FACS analyses
  • Cytokines (e.g. IL-6), growth factors (e.g. EGF) etc.
  • Cell cycle analyses, cytotoxicity by measuring PI staining
  • Transmembrane potential of the mitochondria, calcium and pH mobilization
  • Reactive oxygen species (ROS)
  • Caspases (3, 7, 8, 6 and 9) activity by Flow cytometry and western blots
  • Bcl-2, Bcl-X, Bax, Bid and cytoplasmic cytochrome C by western blots and PCR.
  • In vitro assays for tubulin polymerization.
  • Activation of Transcription Factors
  • Signaling studies MAPKs, IKK

Other cellular & molecular models are available upon request.

 Our immunomodulatory activity analysis portfolio provides a remarkably interesting platform to study and understand the effects of single molecules/herbal and plant extracts, nano particles, ayurvedic drugs on primary immune cells like T lymphocytes, B lymphocytes, NK cells, monocyte/macrophages and other cells of immune system. The experimentations of immunomodulatory portfolio help in understanding the effects on activation and functionality of different T cell subsets (Th1, Th2, Th17, Tregs, Cytotoxic T cells, memory, and naïve T cells), effects on B cell parameters, effects on NK cell and macrophage activity, effects on cytokine/chemokine secretion, effectors of various inflammatory signaling pathways & mediators and finally study the effects on In Vitro differentiation of immune cells.

Our regenerative medicine testing portfolio gives a unique opportunity to test single molecules/herbal and plant extracts, nano particles, ayurvedic drugs on stem cells for their function ad regenerative capabilities. Logical Life Science Pvt Ltd specializes in growing and characterizing mesenchymal stem cells from bone marrow and oral cavity. Additionally, we have the expertise in In vitro differentiation of mesenchymal stem cells into bone cells, cartilage cells, adipocytes, and other target cell types. We test  drugs on all the aspects of dental pulp stem cells (DPSCs), periodontal ligament stem cells, Gingival stem cells and bone marrow derived mesenchymal stem cells including their effect on proliferation, regeneration potential, stemness, and differentiation potential. 

Logical Life Science Pvt Ltd offers the full service to assess prophylactic and acute therapeutic effects of oral care products. Our cellular models can be used for
testing single chemical identities or diverse galenic formulations. We provides various models
and methods
• Human primary cultures (monocytes, gingival and periodontal
ligament fibroblasts, and keratinocytes to determine all relevant parameters (e.g. inflammation) linked to gingivitis and
periodontitis
• Capsaicin and menthol receptors (TPRV-1 and CMR1) heterologous transfected cells (artificial tongue)
• Cell proliferation and cell cycle
analysis
• Mitochondrial function and oxidative stress Phagocytosis and
Autophagy
• Lectin binding assay: Studying
the effect of ingredients on lectin binding to avoid bacterial
adherence.

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Our Solutions

Collaborative Research

After the advent of various techniques related to cellular analysis, the research in the field of biology, life sciences, and medicine is becoming more and more technology-driven. The research fraternity is now more focused on generating the quantifiable data of all the parameters required to analyze the cells. Logical life science Pvt Ltd is a dedicated cellular research and analysis lab that is committed to providing an extension to the ongoing research of scientists, professors, Postdoctoral and Ph.D. students through its unique collaborative research programe.

Researchers from various fields of biology and medicine like cancer biology, stem cell biology, immunology, cell biology, regenerative medicine, pathology, and molecular biology can take advantage of our facilities of automated multi-color flow cytometry, automatic magnetic cell sorting, human and animal cell culture, mice experimentation facility and many more modern experimentation systems by becoming our research partners. The laboratory and experimental systems provided by Logical life sciences PVT ltd can be utilized by researchers as an extended arm of their own research to make their studies more complex, more impactful, and more quantifiable. Our lab is focused on providing full intellectual and technical support to both budding and well-established research groups.

Benefits –

  1. By becoming research partners with Logical Life Sciences Pvt Ltd, researchers gain full access to the state of the art technologies of cellular research like multi-color flow cytometry, cell sorting, cell culture, In vitro differentiation, anti-cancer activity analysis, anti-inflammatory activity analysis, drug screening, and gene expression analysis.
  2. Researchers do their experiments and are trained with hands-on experience on all the experimental platforms, theoretical analysis, mathematical and statistical analysis.
  3. Researchers and students have full access to all the software related to the various technical platforms.
  4. Based on the requirement, researchers are provided with support in scientific data writing and creating publication grade figures, thesis preparation, and scientific article writing.
  5. Most of our technologies are agonistic to applications, meaning they can be used to address questions in a wide range of life science disciplines.

Writing Services

  • Research Proposals
  • Research presentation
  • Research paper writing
  • Review paper writing
  • Grant application writing
  • Ph.D thesis writing
  • Statistical analysis
  • Plagiarism checking
  • Grammar checking
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Timeline for publication of research articles

  • Day 1

    Translation

  • Day 4

    Review & Approve

  • Day 5

    Project Start

  • Day 13

    1. Initial Certification + Outline
  • Day 18

    2. Review  & Respond

  • Day 26

    Draft 1 + Journal Selection

  • Day 28

    Review , Revise & Select Journal

  • Day 36

    Draft 2 + Submission  Request 

  • Day 40

    Review , Revise & Respond

  • Day 46

    Final Draft + PlagCheck

  • Day 47

    Review & Approve

  • Day 55

    Editing + Artwork + Finalized File

  • Day 57

    Review & Revise

  • Day 60

    General PDF proof 

  • Day 61

    Review & Approve

  • Day 62

    Complete Submision 

  • Day 62

    Project End