Our anti-cancer activity analysis portfolio gives a wide array of experimental choices to the researchers, pharma companies and drug designing/manufacturing companies where they can test the anticancer activities of single molecules/herbal and plant extracts, nano particles, ayurvedic drugs on various cancer cells lines as well as on primary tumor cells of various origins. In our basic anticancer activity analysis portfolio molecules/abstracts can be tested for their effects on cell death (Apoptosis), cell proliferation, cell cycle, free radical generation, and other basic experiments.
Our specialized anticancer activity analysis portfolio tests and screens the drugs/extracts for their activities against cancer stem cell markers, metastatic parameters, effects on epithelial-mesenchymal transitions and effects on tumor immune evasion mechanisms.
The parameters we study are
Other cellular & molecular models are available upon request.
Our immunomodulatory activity analysis portfolio provides a remarkably interesting platform to study and understand the effects of single molecules/herbal and plant extracts, nano particles, ayurvedic drugs on primary immune cells like T lymphocytes, B lymphocytes, NK cells, monocyte/macrophages and other cells of immune system. The experimentations of immunomodulatory portfolio help in understanding the effects on activation and functionality of different T cell subsets (Th1, Th2, Th17, Tregs, Cytotoxic T cells, memory, and naïve T cells), effects on B cell parameters, effects on NK cell and macrophage activity, effects on cytokine/chemokine secretion, effectors of various inflammatory signaling pathways & mediators and finally study the effects on In Vitro differentiation of immune cells.
Our regenerative medicine testing portfolio gives a unique opportunity to test single molecules/herbal and plant extracts, nano particles, ayurvedic drugs on stem cells for their function ad regenerative capabilities. Logical Life Science Pvt Ltd specializes in growing and characterizing mesenchymal stem cells from bone marrow and oral cavity. Additionally, we have the expertise in In vitro differentiation of mesenchymal stem cells into bone cells, cartilage cells, adipocytes, and other target cell types. We test drugs on all the aspects of dental pulp stem cells (DPSCs), periodontal ligament stem cells, Gingival stem cells and bone marrow derived mesenchymal stem cells including their effect on proliferation, regeneration potential, stemness, and differentiation potential.
Logical Life Science Pvt Ltd offers the full service to assess prophylactic and acute therapeutic effects of oral care products. Our cellular models can be used for
testing single chemical identities or diverse galenic formulations. We provides various models
• Human primary cultures (monocytes, gingival and periodontal
ligament fibroblasts, and keratinocytes to determine all relevant parameters (e.g. inflammation) linked to gingivitis and
• Capsaicin and menthol receptors (TPRV-1 and CMR1) heterologous transfected cells (artificial tongue)
• Cell proliferation and cell cycle
• Mitochondrial function and oxidative stress Phagocytosis and
• Lectin binding assay: Studying
the effect of ingredients on lectin binding to avoid bacterial
Researchers from various fields of biology and medicine like cancer biology, stem cell biology, immunology, cell biology, regenerative medicine, pathology, and molecular biology can take advantage of our facilities of automated multi-color flow cytometry, automatic magnetic cell sorting, human and animal cell culture, mice experimentation facility and many more modern experimentation systems by becoming our research partners. The laboratory and experimental systems provided by Logical life sciences PVT ltd can be utilized by researchers as an extended arm of their own research to make their studies more complex, more impactful, and more quantifiable. Our lab is focused on providing full intellectual and technical support to both budding and well-established research groups.
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